Fenofibric acid | PPAR agonist | Probechem Biochemicals

Chemical Structure : Fenofibric acid

CAS No.: 42017-89-0

Fenofibric acid (FNF acid)

Catalog No.: PC-23809Not For Human Use, Lab Use Only.

Fenofibric acid, an active metabolite of fenofibrate and anti-inflammatory agent, is a PPAR activitor, with EC50s of 22.4 µM, 1.47 µM, and 1.06 µM for PPARα, PPARγ and PPARδ, respectively, also inhibits COX-2 with IC50 of 48 nM.

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Biological Activity

Fenofibric acid, an active metabolite of fenofibrate and anti-inflammatory agent, is a PPAR activitor with EC50s of 22.4 µM, 1.47 µM, and 1.06 µM for PPARα, PPARγ and PPARδ, respectively, also inhibits COX-2 with IC50 of 48 nM.

Physicochemical Properties

M.Wt	318.75
Formula	C17H15ClO4
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic acid

References

1. Dietz M, et al. ChemMedChem. 2012 Jun;7(6):1101-11.

2. Prasad GS, et al. Inflammopharmacology. 2017 Dec 13.

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Fenofibric acid (FNF acid)

Biological Activity

Physicochemical Properties

References

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