Welcome to Shanghai Probechem Biochemicals Co Ltd !Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : LDT409
Catalog No.: PC-22386Not For Human Use, Lab Use Only.
LDT409 is a small molecule, orally active partial agonist of pan PPARα/γ/δ with EC50 of 0.5 uM, 0.9 uM and 33 uM for huamn PPARα and PPARγ, respectively.
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
LDT409 is a small molecule, orally active partial agonist of pan PPARα/γ/δ with EC50 of 0.5 uM, 0.9 uM and 33 uM for huamn PPARα and PPARγ, respectively.
LDT409 activates PPARα target genes in primary hepatocytes in a gene-selective manner.
LDT409 differentially regulate the expression of PPARγ target genes and adipocyte differentiation in 3T3-L1 cells.
LDT409 demonstrates tissue-specific activation of PPARα and PPARγ in an in vivo zebrafish embryo model.
LDT409 reverses HFD-induced weight gain back to chow-fed control levels, improves glucose homeostasis and plasma lipids in HFD-fed mice.
| M.Wt | 390.61 | |
| Formula | C25H42O3 | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
