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PPARα activator compound 3

Chemical Structure : PPARα activator compound 3

CAS No.: 1011399-77-1

PPARα activator compound 3

Catalog No.: PC-35153Not For Human Use, Lab Use Only.

PPARα activator compound 3 is a specific PPAR activator that selectively up-regulates PPARα transcriptional activity, leading to PPARα target gene expression both in vitro and in vivo.

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    Biological Activity

    PPARα activator compound 3 is a specific PPAR activator that selectively up-regulates PPARα transcriptional activity, leading to PPARα target gene expression both in vitro and in vivo.
    PPARα activator compound 3 reduces plasma triglyceride levels with similar efficiency as fenofibrate in high fructose-fed rats.

    Physicochemical Properties

    M.Wt 339.37
    Formula C19H18FN3O2
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    6-cyclopropyl-1-(4-fluorophenyl)-3-isopropyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid

    References

    1. Tachibana K, et al. J Biol Chem. 2018 May 15. pii: jbc.RA118.002077.

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