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SR16832

Chemical Structure : SR16832

CAS No.: 2088135-12-8

SR16832 (SR-16832, SR 16832)

Catalog No.: PC-62344Not For Human Use, Lab Use Only.

SR16832 is a dual-site, covalent and allosteric antagonist of PPARγ, inhibits cellular allosteric activation of PPARγ by rosiglitazone.

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10 mg $128 In stock
25 mg $218 In stock
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100 mg $528 In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

SR16832 is a dual-site, covalent and allosteric antagonist of PPARγ, inhibits cellular allosteric activation of PPARγ by rosiglitazone.
SR16832 is a useful, complementary chemical tools for researchers to use to simultaneously inhibit both orthosteric and allosteric ligand-induced cellular activation of PPARγ.

Physicochemical Properties

M.Wt 357.75
Formula C17H12ClN3O4
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-chloro-N-(6-methoxyquinolin-4-yl)-5-nitrobenzamide

References

1. Brust R, et al. ACS Chem Biol. 2017 Apr 21;12(4):969-978.

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