FX-909 | PPARγ inhibitor | Probechem Biochemicals

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Chemical Structure : FX-909

FX-909 (FX909, FX 909)

Catalog No.: PC-20667Not For Human Use, Lab Use Only.

FX-909 (FX909) is a potent, selective and covalent peroxisome proliferator-activated receptor gamma (PPARG, PPARγ) inhibitor with cellular IC50 of 1 nM, >2000-fold selective over PPARα/PPARδ.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

FX-909 (FX909) is a potent, selective and covalent peroxisome proliferator-activated receptor gamma (PPARG, PPARγ) inhibitor with cellular IC50 of 1 nM, >2000-fold selective over PPARα/PPARδ.

Physicochemical Properties

M.Wt	361.32
Formula	C16H9F2N3O3S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	FC1=C2C(NC(C3=C(C=CC(C#N)=N3)S(C)(=O)=O)=CC2=O)=CC(F)=C1

References

1. Jennifer A. Mertz, et al. Cancer Res (2023) 83 (7_Supplement): 2802.

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FX-909 (FX909, FX 909)

Biological Activity

Physicochemical Properties

References

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