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FX-909

Chemical Structure : FX-909

CAS No.: 2924573-90-8

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FX-909 (FX909, FX 909)

Catalog No.: PC-20667Not For Human Use, Lab Use Only.

FX-909 (FX909) is a potent, selective and covalent peroxisome proliferator-activated receptor gamma (PPARG, PPARγ) inverse agonist with cellular IC50 of 1 nM, >2000-fold selective over PPARα/PPARδ.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

FX-909 (FX909) is a potent, selective and covalent peroxisome proliferator-activated receptor gamma (PPARG, PPARγ) inverse agonist with cellular IC50 of 1 nM, >2000-fold selective over PPARα/PPARδ.

Physicochemical Properties

M.Wt 360.33
Formula C17H10F2N2O3S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

3-(5,7-Difluoro-4-oxo-1,4-dihydroquinolin-2-yl)-4-(methylsulfonyl)benzonitrile

References

1. Jennifer A. Mertz, et al. Cancer Res (2023) 83 (7_Supplement): 2802.

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