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FX-909

Chemical Structure : FX-909

CAS No.: 2902611-05-4

FX-909 (FX909, FX 909)

Catalog No.: PC-20667Not For Human Use, Lab Use Only.

FX-909 (FX909) is a potent, selective and covalent peroxisome proliferator-activated receptor gamma (PPARG, PPARγ) inhibitor with cellular IC50 of 1 nM, >2000-fold selective over PPARα/PPARδ.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    FX-909 (FX909) is a potent, selective and covalent peroxisome proliferator-activated receptor gamma (PPARG, PPARγ) inhibitor with cellular IC50 of 1 nM, >2000-fold selective over PPARα/PPARδ.

    Physicochemical Properties

    M.Wt 361.32
    Formula C16H9F2N3O3S
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    6-(5,7-difluoro-4-oxo-1,4-dihydroquinolin-2-yl)-5-(methylsulfonyl)picolinonitrile

    References

    1. Jennifer A. Mertz, et al. Cancer Res (2023) 83 (7_Supplement): 2802.

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