Chemical Structure : Alisertib
CAS No.:
1028486-01-2
Alisertib
(MLN 8237;MLN8237;MLN-8237)
Catalog No. : PC-42757Not For Human Use, Lab Use Only.
Alisertib (MLN8237) is a potent and highly selective inhibitor of Aurora A (AURKA) with IC50 of 1.2 nM.
Packing Price Stock Quantity 5 mg $58 In stock 0 1 2 3 4 5 10 mg $88 In stock 0 1 2 3 4 5 25 mg $138 In stock 0 1 2 3 4 5 50 mg $218 In stock 0 1 2 3 4 5 100 mg Get quote 0 1 2 3 4 5
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-4275701
Biological Activity
Alisertib (MLN8237) is a potent and highly selective inhibitor of Aurora A (AURKA) with IC50 of 1.2 nM.
Physicochemical Properties
M.Wt
518.9235
Formula
C27H20ClFN4O4
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
DMSO: 9.33 mg/mL
Chemical Name/SMILES
Benzoic acid, 4-[[9-chloro-7-(2-fluoro-6-methoxyphenyl)-5H-pyrimido[5,4-d][2]benzazepin-2-yl]amino]-2-methoxy-
References
1. Manfredi MG, et al. Clin Cancer Res
2. Wen Q, et al. Cell.
3. Zhou N, et al. Clin Cancer Res
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