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Allopregnanolone

Chemical Structure : Allopregnanolone

CAS No.: 516-54-1

Allopregnanolone (ALLO, Brexanolone)

Catalog No.: PC-28339Not For Human Use, Lab Use Only.

Allopregnanolone (ALLO) is an endogenous neuroactive steroid, has antidepressant and anxiolytic activity, is a positive allosteric modulator of the GABAA receptor.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Allopregnanolone (ALLO) is an endogenous neuroactive steroid, has antidepressant and anxiolytic activity, is a positive allosteric modulator of the GABAA receptor.

Physicochemical Properties

M.Wt 318.50
Formula C21H34O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1-((3R,5S,8R,9S,10S,13S,14S,17S)-3-hydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)ethan-1-one

References

1. Monnet FP, et al. J Pharmacol Sci. 2006 Feb;100(2):93-118.

3. Pinna G, et al. Neurochem Res. 2008 Oct;33(10):1990-2007.

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