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Chemical Structure : Almorexant
CAS No.: 871224-64-5
Catalog No.: PC-42704Not For Human Use, Lab Use Only.
Almorexant (ACT-078573) is a potent, dual Orexin receptor OX1/OX2 antagonist with Ki of 1.3/0.17 nM for hOX1/hOX2 respectively.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $118 | In stock | |
| 10 mg | $188 | In stock | |
| 25 mg | $298 | In stock | |
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| 100 mg | Get quote |
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Almorexant (ACT-078573) is a potent, dual Orexin receptor OX1/OX2 antagonist with Ki of 1.3/0.17 nM for hOX1/hOX2 respectively.
Almorexant selectively inhibits the functional consequences of OX1 and OX2 receptor activation, such as intracellular Ca2+ mobilization.
| M.Wt | 512.5632 | |
| Formula | C29H31F3N2O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
2(1H)-Isoquinolineacetamide, 3,4-dihydro-6,7-dimethoxy-N-methyl-α-phenyl-1-[2-[4-(trifluoromethyl)phenyl]ethyl]-, (αR,1S)- |
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1. Malherbe P, et al. Mol Pharmacol. 2009 Sep;76(3):618-31.
2. Malherbe P, et al. Mol Pharmacol. 2010 Jul;78(1):81-93.
3. Li A, et al. J Physiol. 2010 Aug 1;588(Pt 15):2935-44.
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