Alogliptin | DPP-4 inhibitor | Probechem Biochemicals

Chemical Structure : Alogliptin

CAS No.: 850649-61-5

Alogliptin (SYR-322 free base)

Catalog No.: PC-23796Not For Human Use, Lab Use Only.

Alogliptin (SYR-322 free base) is a potent, selective and orally active inhibitor of DPP-4 with IC50 of <10 nM, >10,000-fold selectivity over DPP-8 and DPP-9.

Packing	Price	Stock
5 mg	$68	In stock
10 mg	$98	In stock
25 mg	$158	In stock
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Biological Activity

Alogliptin (SYR-322 free base) is a potent, selective and orally active inhibitor of DPP-4 with IC50 of <10 nM, >10,000-fold selectivity over DPP-8 and DPP-9.

Physicochemical Properties

M.Wt	339.40
Formula	C18H21N5O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(R)-2-((6-(3-Aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)benzonitrile

References

1. Feng J, et al. J Med Chem. 2007 May 17;50(10):2297-300.

2. Thomas L, et al. J Pharmacol Exp Ther. 2008 Apr;325(1):175-82.

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Alogliptin (SYR-322 free base)

Biological Activity

Physicochemical Properties

References

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