| Cat. No. |
Product Name |
Information |
| PC-20348 |
Sitagliptin phosphate
DPP-4 inhibitor
|
Sitagliptin phosphate (MK-0431, MK0431) is a potent, orally active dipeptidyl peptidase IV (DPP4) inhibitor with IC50 of 18 nM. |
| PC-20220 |
AX8819
DPP-2 inhibitor
|
AX8819 is a potent, specific DPP-2 inhibitor with IC50 of 0.88 nM, highly selective for DPP II over all of the other DPP enzymes. |
| PC-49843 |
1G244
DPP8/9 inhibitor
|
1G244 is a potent and selective DPP8/9 inhibitor with IC50 of 14/53 nM and Ki of 0.9/4.2 nM, respectively. |
| PC-49298 |
ICeD-1
DPP9 inhibitor
|
ICeD-1 is a potent DPP9 inhibitor capable of killing HIV-1 infected peripheral blood mononuclear cells, activates the caspase recruitment domain family member 8 (CARD8) inflammasome. |
| PC-49297 |
ICeD-2
DPP9 inhibitor
|
ICeD-2 is a potent dipeptidyl peptidase 9 (DPP9) inhibitor capable of killing HIV-1 infected peripheral blood mononuclear cells, activates the caspase recruitment domain family member 8 (CARD8) inflammasome. |
| PC-49042 |
MK-0626
DPP-4 inhibitor
|
MK-0626 (MK-626) is a potent, selective and orally active DPP-4 inhibitor (IC50=6.3 nM) with excellent selectivity. |
| PC-72074 |
BR102910
FAP inhibitor
|
BR102910 (BR 102910) is a novel potent, selective, oral fibroblast activation protein (FAP) inhibitor with IC50 of 1 nM. |
| PC-72073 |
BR103354
FAP inhibitor
|
BR103354 (BR 103354) is a novel potent, selective, oral fibroblast activation protein (FAP) inhibitor with IC50 of 14 nM. |
| PC-36075 |
UAMC-1110
FAP inhibitor
|
UAMC-1110 (UAMC1110) is a potent, selective small molecule inhibitor of fibroblast activation protein (FAP) with IC50 of 3.2 nM. |
| PC-35918 |
KR-62436
DPP-4 inhibitor
|
KR-62436 (KR62436) is a potent, selective DPP4 inhibitor with IC50 of 0.78, 0.49, 0.14 uM for rat plasma, porcine kidney, human DPP4 (Caco-2), respectively. |
| PC-63358 |
TAK-100
DPP-4 inhibitor
|
TAK-100 is a potent, selective and orally active inhibitor of DPP-4 with IC50 of 5.3 nM, shows no inhibition on DPP2/8/9.. |
| PC-50014 |
Talabostat
DPP4 inhibitor
|
Talabostat (PT-100, Val-boroPro) is a potent, nonselective, orally available inhibitor of post-proline cleaving serine proteases with Ki of 0.18 nM for DPP4, also potently inhibits DPP8/9 (IC50=1.5/0.76 nM), FAP, DPP2 and some other DASH family enzymes. |
