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Sitagliptin phosphate

Chemical Structure : Sitagliptin phosphate

CAS No.: 654671-78-0

Sitagliptin phosphate (MK-0431, MK0431)

Catalog No.: PC-20348Not For Human Use, Lab Use Only.

Sitagliptin phosphate (MK-0431, MK0431) is a potent, orally active dipeptidyl peptidase IV (DPP4) inhibitor with IC50 of 18 nM.

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Biological Activity

Sitagliptin phosphate (MK-0431, MK0431) is a potent, orally active dipeptidyl peptidase IV (DPP4) inhibitor with IC50 of 18 nM.

Physicochemical Properties

M.Wt 505.31
Formula C16H18F6N5O5P
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(R)-3-amino-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butan-1-one Phosphate

References

1. Dooseop Kim, et al. J Med Chem. 2005 Jan 13;48(1):141-51.

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