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Alogliptin benzoate

Chemical Structure : Alogliptin benzoate

CAS No.: 850649-62-6

Alogliptin benzoate (SYR 322)

Catalog No.: PC-23797Not For Human Use, Lab Use Only.

Alogliptin benzoate (SYR-322) is a potent, selective and orally active inhibitor of DPP-4 with IC50 of <10 nM, >10,000-fold selectivity over DPP-8 and DPP-9.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Alogliptin benzoate (SYR-322) is a potent, selective and orally active inhibitor of DPP-4 with IC50 of <10 nM, >10,000-fold selectivity over DPP-8 and DPP-9.

Physicochemical Properties

M.Wt 461.52
Formula C25H27N5O4
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(R)-2-((6-(3-Aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)benzonitrile benzoate

References

1. Feng J, et al. J Med Chem. 2007 May 17;50(10):2297-300.

2. Thomas L, et al. J Pharmacol Exp Ther. 2008 Apr;325(1):175-82.

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