Chemical Structure : Alvespimycin hydrochloride
CAS No.:
467214-21-7
Alvespimycin hydrochloride
(17-DMAG, KOS-1022, NSC 707545)
Catalog No. : PC-42839Not For Human Use, Lab Use Only.
Alvespimycin hydrochloride (17-DMAG) is a potent, orally bioavailable Hsp90 inhibitor with binding EC50 of 62 nM.
Packing Price Stock Quantity 25 mg $88 In stock 0 1 2 3 4 5 50 mg $138 In stock 0 1 2 3 4 5 100 mg $218 In stock 0 1 2 3 4 5 250 mg Get quote 0 1 2 3 4 5
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-4283901
Biological Activity
Alvespimycin hydrochloride (17-DMAG) is a potent, orally bioavailable Hsp90 inhibitor with binding EC50 of 62 nM.
Physicochemical Properties
M.Wt
653.2065
Formula
C32H49ClN4O8
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
DMSO: ≥ 50 mg/mL
Chemical Name/SMILES
Geldanamycin, 17-demethoxy-17-[[2-(dimethylamino)ethyl]amino]-, hydrochloride (1:1)
References
1. Bull EE, et al. Clin Cancer Res.
2. Kaur G, et al. Clin Cancer Res
3. Ge J, et al. J Med Chem
Contact Us
sales@probechem.com
