Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.
EN | CN

You are here:Home-Chemical Inhibitors & Agonists-Others-Other Targets-Amcasertib
Amcasertib

Chemical Structure : Amcasertib

CAS No.: 1129403-56-0

Amcasertib (BBI-503, BBI503)

Catalog No.: PC-45384Not For Human Use, Lab Use Only.

Amcasertib (BBI503) is a small-molecule inhibitor that inhibits Nanog and other CSC (cancer stem cells) pathways by targeting kinases.

Packing Price Stock Quantity
5 mg $118 In stock
10 mg $188 In stock
25 mg $328 In stock
50 mg Get quote
100 mg Get quote

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Amcasertib (BBI503) is a small-molecule inhibitor that inhibits Nanog and other CSC (cancer stem cells) pathways by targeting kinases.
Amcasertib targets and inhibits one or more pathways involved in cancer stem cell survival, shows potential antineoplastic activity.

Physicochemical Properties

M.Wt 539.691
Formula C31H33N5O2S
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: ≥ 30 mg/mL

Chemical Name/SMILES

1H-Pyrrole-3-carboxamide, N-[2-(diethylamino)ethyl]-5-[[1,2-dihydro-2-oxo-5-(2-phenyl-4-thiazolyl)-3H-indol-3-ylidene]methyl]-2,4-dimethyl-

References

1. Marcucci F, et al. Front Oncol. 2016 May 10;6:115.

2. Iv Santaliz-Ruiz LE, et al. Int J Cancer. 2014 Dec 15;135(12):2741-8.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

Get Quote

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • Additional Information: