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Amifostine

Chemical Structure : Amifostine

CAS No.: 20537-88-6

Amifostine (WR2721)

Catalog No.: PC-26155Not For Human Use, Lab Use Only.

Amifostine (WR2721) is a broad-spectrum cytoprotective agent and a radioprotector, protects normal tissues from damage caused by radiation and chemotherapy, also is potent hypoxia-inducible factor-α1 (HIF-α1) and p53 inducer.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Amifostine (WR2721) is a broad-spectrum cytoprotective agent and a radioprotector, protects normal tissues from damage caused by radiation and chemotherapy, also is potent hypoxia-inducible factor-α1 (HIF-α1) and p53 inducer.

Physicochemical Properties

M.Wt 214.22
Formula C5H15N2O3PS
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

S-(2-((3-Aminopropyl)amino)ethyl) O,O-dihydrogen phosphorothioate

References

1. Kouvaris, J.R. et al. Oncologist, 2007. 12(6): p. 738-47.

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