Amifostine thiol | Radioprotector | Probechem Biochemicals

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Chemical Structure : Amifostine thiol

CAS No.: 31098-42-7

Amifostine thiol (Amitiotine, WR-1065)

Catalog No.: PC-26154Not For Human Use, Lab Use Only.

Amifostine thiol (Amitiotine, WR-1065) is an active metabolite of the cytoprotector Amifostine, which is a broad-spectrum cytoprotective agent and a radioprotector, activates p53 through a JNK-dependent signaling pathway.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Physicochemical Properties

M.Wt	134.24
Formula	C5H14N2S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(3-Aminopropylamino)ethanethiol

References

1. Jaroslaw Dziegielewski, et al. Free Radic Biol Med. 2008 Dec 15; 45(12): 1674-1681.

2. Olivier Pluquet, et al. J Biol Chem. 2003 Apr 4;278(14):11879-87. J Biol Chem. 2003 Apr 4;278(14):11879-87.

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Amifostine thiol (Amitiotine, WR-1065)

Biological Activity

Physicochemical Properties

References

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