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Antabactin

Chemical Structure : Antabactin

CAS No.: 2570821-88-2

Antabactin

Catalog No.: PC-73278Not For Human Use, Lab Use Only.

Antabactin (ANT) is a highly potent pan-abscisic acid (ABA) receptor antagonist with EC50 of 760 nM and picomolar dissociation constant, disrupts signaling by preventing receptor-PP2C interactions.

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    Biological Activity

    Antabactin (ANT) is a highly potent pan-abscisic acid (ABA) receptor antagonist with EC50 of 760 nM and picomolar dissociation constant, disrupts signaling by preventing receptor-PP2C interactions.
    Antabactin binds to Arabidopsis receptors range from ∼400 to 1,700 pM.
    Antabactin displays improved activity in vivo and disrupts ABA-mediated processes in multiple species compared to PanMe and AA1.
    Antabactin is able to accelerate seed germination in Arabidopsis, tomato, and barley, suggesting that it could be useful as a germination stimulant in species where endogenous ABA signaling limits seed germination.

    Physicochemical Properties

    M.Wt 610.69
    Formula C34H35FN6O4
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    1-(2-(3,5-dicyclopropyl-4-(4-((6-fluoroquinoline-2-carboxamido)methyl)-1H-1,2,3-triazol-1-yl)phenyl)acetamido)cyclohexane-1-carboxylic acid

    References

    1. Aditya S Vaidya, et al. Proc Natl Acad Sci U S A. 2021 Sep 21;118(38):e2108281118.

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