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Chemical Structure : Antitrypanosomal agent 10
Catalog No.: PC-21377Not For Human Use, Lab Use Only.
Antitrypanosomal agent 10 is a potent, orally active antitrypanosomal compound, selectively inhibits the growth of parasites T. b. brucei, T. b. gambiense and T. b. rhodesiense with EC50 of 0.54, 0.13 and 1.14 uM, resepctively.
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Antitrypanosomal agent 10 is a potent, orally active antitrypanosomal compound, selectively inhibits the growth of parasites T. b. brucei, T. b. gambiense and T. b. rhodesiense with EC50 of 0.54, 0.13 and 1.14 uM, resepctively.
Antitrypanosomal agent 10 has excellent oral bioavailability and (100 mpk) is effective in treating acute infection of Human African Trypanosomiasis (HAT) in mouse models.
| M.Wt | 269.28 | |
| Formula | C10H11N3O4S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Ajayi O, et al. Eur J Med Chem. 2023 Nov 15;263:115954.
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