Chemical Structure : Arcyriaflavin A
CAS No.: 118458-54-1
Catalog No.: PC-23981Not For Human Use, Lab Use Only.
Arcyriaflavin A is a potent inhibitor of the cyclin D1/CDK4 complex with IC50 of 140 nM, also inhibits CaMKII with IC50 of 25 nM, suppresses tumor growth, migration, and invasion of metastatic melanoma cells.
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Arcyriaflavin A is a potent inhibitor of the cyclin D1/CDK4 complex with IC50 of 140 nM, also inhibits CaMKII with IC50 of 25 nM, suppresses tumor growth, migration, and invasion of metastatic melanoma cells.
M.Wt | 325.33 | |
Formula | C20H11N3O2 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
5H-Indolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7(6H)-dione, 12,13-dihydro- |
1. P A Horton, et al. Experientia. 1994 Sep 15;50(9):843-5.
2. Sanchez-Martinez C, et al. Bioorg Med Chem Lett. 2003 Nov 3;13(21):3835-9.
3. Kim D, et al. Cancer Cell Int. 2025 Feb 13;25(1):42.
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