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Artemisinin

Chemical Structure : Artemisinin

CAS No.: 63968-64-9

Artemisinin (Qinghaosu, NSC 369397)

Catalog No.: PC-23278Not For Human Use, Lab Use Only.

Artemisinin (Qinghaosu) is a sesquiterpene lactone, an anti-malarial agent isolated from the aerial parts of Artemisia annua L., potently inhibits PfPI3K.

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Biological Activity

Artemisinin (Qinghaosu) is a sesquiterpene lactone, an anti-malarial agent isolated from the aerial parts of Artemisia annua L., potently inhibits PfPI3K.
Artemisinin (Qinghaosu) inhibits AKT signaling pathway by decreasing pAKT in a dose-dependent manner. Artemisinin (Qinghaosu) reduces cancer cell proliferation, migration, invasion, tumorigenesis and metastasis and has neuroprotective effects.

Physicochemical Properties

M.Wt 282.34
Formula C15H22O5
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(3R,5aS,6R,8aS,9R,12S,12aR)-3,6,9-Trimethyloctahydro-12H-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10(3H)-one

References

1. Lin SP, et al. Front Cell Neurosci. 2018 Apr 20;12:108.

2. Mbengue A, et al. Nature. 2015 Apr 30;520(7549):683-7.

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