Arterolane |CAS:664338-39-0 Probechem Biochemicals

Chemical Structure : Arterolane

Catalog No.: PC-62988Not For Human Use, Lab Use Only.

Arterolane (OZ277.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Arterolane (OZ277;RBx 11160) is an antimalarial ozonide for treatment of acute uncomplicated falciparum malaria.

Parasite Infection

Phase 2 Discontinued

M.Wt	392.54
Formula	C22H36N2O4
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(2-amino-2-methylpropyl)-2-{dispiro[adamantane-2,2'-[1,3,5]trioxolane-4',1''-cyclohexane]-4''-yl}acetamide

1. Kreidenweiss A, et al. Antimicrob Agents Chemother. 2006 Apr;50(4):1535-7.

2. Vennerstrom JL, et al. Nature. 2004 Aug 19;430(7002):900-4.

3. Maerki S, et al. J Antimicrob Chemother. 2006 Jul;58(1):52-8.

4. Snyder C, et al. Exp Parasitol. 2007 Mar;115(3):296-300.