AstraZeneca CCR4 antagonist

Chemical Structure : AstraZeneca CCR4 antagonist

Catalog No.: PC-73266Not For Human Use, Lab Use Only.

AstraZeneca CCR4 antagonist is a potent, selective CCR4 antagonist, inhibits CCR4 ligand macrophage-derived chemokine (MDC/CCL22) in CCR4+CD4+ T cells.

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Biological Activity

AstraZeneca CCR4 antagonist is a potent, selective CCR4 antagonist, inhibits CCR4 ligand macrophage-derived chemokine (MDC/CCL22) in CCR4+CD4+ T cells.

Physicochemical Properties

M.Wt	474.737
Formula	C18H14Cl3N3O4S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2,3-dichloro-N-(6-chloro-3-((2-(hydroxymethyl)benzyl)oxy)pyrazin-2-yl)benzenesulfonamide

References

1. G Banfield, et al. Allergy. 2010 Sep;65(9):1126-33.

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