You are here:Home-Chemical Inhibitors & Agonists-Metabolic Enzyme/Protease-Beta-secretase (BACE)-Atabecestat
Atabecestat

Chemical Structure : Atabecestat

CAS No.: 1200493-78-2

Atabecestat (JNJ-54861911;JNJ54861911)

Catalog No.: PC-60507Not For Human Use, Lab Use Only.

Atabecestat (JNJ-54861911, JNJ54861911) is a novel potent beta-secretase (BACE) inhibitor for treatment of Alzheimer's Disease.

Packing Price Stock Quantity
5 mg $358 In stock
10 mg $548 In stock
25 mg Get quote
100 mg Get quote

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Atabecestat (JNJ-54861911, JNJ54861911) is a novel potent, oral beta-secretase (BACE) inhibitor for treatment of Alzheimer's Disease.

Physicochemical Properties

M.Wt 367.4
Formula C18H14FN5OS
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(S)-N-(3-(2-amino-4-methyl-4H-1,3-thiazin-4-yl)-4-fluorophenyl)-5-cyanopicolinamide

References

1. Timmers M, et al. Alzheimers Dement (N Y). 2016 Aug 24;2(3):202-212.

2. Timmers M, et al. J Alzheimers Dis. 2017;56(4):1437-1449.

3. Timmers M, et al. J Clin Pharmacol. 2018 Mar 5. doi: 10.1002/jcph.1087. 

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

Get Quote

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • Additional Information: