Chemical Structure : Atabecestat
CAS No.: 1200493-78-2
Catalog No.: PC-60507Not For Human Use, Lab Use Only.
Atabecestat (JNJ-54861911, JNJ54861911) is a novel potent beta-secretase (BACE) inhibitor for treatment of Alzheimer's Disease.
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Atabecestat (JNJ-54861911, JNJ54861911) is a novel potent, oral beta-secretase (BACE) inhibitor for treatment of Alzheimer's Disease.
M.Wt | 367.4 | |
Formula | C18H14FN5OS | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
(S)-N-(3-(2-amino-4-methyl-4H-1,3-thiazin-4-yl)-4-fluorophenyl)-5-cyanopicolinamide |
1. Timmers M, et al. Alzheimers Dement (N Y). 2016 Aug 24;2(3):202-212.
2. Timmers M, et al. J Alzheimers Dis. 2017;56(4):1437-1449.
3. Timmers M, et al. J Clin Pharmacol. 2018 Mar 5. doi: 10.1002/jcph.1087.
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