Autotaxin-IN-13 | Autotaxin inhibitor | Probechem Biochemicals

Chemical Structure : Autotaxin-IN-13

Autotaxin-IN-13 (ATX-i)

Catalog No.: PC-72882Not For Human Use, Lab Use Only.

Autotaxin-IN-13 ( ATX-i) is a highly potent, selective Autotaxin inhibitor with IC50 of 6 nM.

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Biological Activity

Autotaxin-IN-13 ( ATX-i) is a highly potent, selective Autotaxin inhibitor with IC50 of 6 nM.
Autotaxin showed sufficient oral bioavailability and low plasma clearance in vivo as well as a suitable half-life to allow for bid or food admix dosing.

Physicochemical Properties

M.Wt	475.428
Formula	C22H20F3N5O4
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	4-(trifluoromethoxy)benzyl (3aS,6aS)-5-(1H-benzo[d][1,2,3]triazole-5-carbonyl)hexahydropyrrolo[3,4-c]pyrrole-2(1H)-carboxylate

References

1. Daniel Hunziker, et al. Front Pharmacol. 2022 Jan 18;12:699535.

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Autotaxin-IN-13 (ATX-i)

Biological Activity

Physicochemical Properties

References

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