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Request The Product List ofAutotaxin Autotaxin

Cat. No. Product Name CAS No. Information
PC-60695

Autotaxin inhibitor compound 1

1619971-30-0 Autotaxin inhibitor compound 1 (Autotaxin-IN-1) is a potent, selective, orally bioavailable inhibitor of autotaxin with IC50 of 2.2 nM in ex vivo human whole blood assay, does not inhibit related proteins ENPP1 and ENPP7.
PC-60640

GWJ-A-23

1351930-95-4 GWJ-A-23 (GWJ-23, GWJ23) is a potent, selective autotaxin inhibitor with Ki of 18 nM, an analog of the known ATX inhibitor S32826 and has improved aqueous solubility compared with the parent compound.
PC-60639

PAT-048

1359983-15-5 PAT-048 (PAT048) is a potent, selective, noncompetitive autotaxin inhibitor with IC50 of 1.1 nM against the lysoPLD activity of human ATX.
PC-60638

PAT-505

1782070-85-2 PAT-505 (PAT 505, PAT505) is a potent, selective, noncompetitive, and orally active autotaxin inhibitor with IC50 of 2.0 nM against the lysoPLD activity of human ATX.
PC-60402

GLPG-1690

1628260-79-6 GLPG-1690 (Ziritaxestat, GLPG1690) is a first-in-class, potent, competitive autotaxin inhibitor with Ki/IC50 of 15 nM/131 nM.
PC-60142

BI-2545

2162961-71-7 BI-2545 is a novel potent, selective, orally available Autotaxin inhibitor with IC50 of 2.1 and 3.4 nM for huamn and rat ATX, respectively.
PC-45610

HA-130

1229652-21-4 A potent and selective inhibitor of autotaxin with IC50 of 28 nM.

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