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Chemical Structure : BIO-32546
CAS No.: 1548743-66-3
Catalog No.: PC-72060Not For Human Use, Lab Use Only.
BIO-32546 (BIO 32546) is a potent, selective, orally bioavailable, brain-penetrable Autotaxin inhibitor with IC50 of 1 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 2 mg | $278 | In stock | |
| 5 mg | $458 | In stock | |
| 10 mg | $758 | In stock | |
| 25 mg | Get quote | ||
| 100 mg | Get quote |
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BIO-32546 (BIO 32546) is a potent, selective, orally bioavailable, brain-penetrable Autotaxin inhibitor with IC50 of 1 nM.
BIO-32546 inhibits plasna hLPA level with IC50 of 53 nM.
| M.Wt | 543.55 | |
| Formula | C28H31F6NO3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO (5.4 mg/mL) |
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| Chemical Name/SMILES |
8-[(1S)-1-[8-(Trifluoromethyl)-7-[[cis-4-(trifluoromethyl)cyclohexyl]oxy]-2-naphthalenyl]ethyl]-8-azabicyclo[3.2.1]octane-3-carboxylic acid |
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1. Bin Ma, et al. ACS Med Chem Lett. 2021 Jun 14;12(7):1124-1129.
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