BIO-32546 | Autotaxin inhibitor | Probechem Biochemicals

Chemical Structure : BIO-32546

CAS No.: 1548743-66-3

BIO-32546 (BIO 32546)

Catalog No.: PC-72060Not For Human Use, Lab Use Only.

BIO-32546 (BIO 32546) is a potent, selective, orally bioavailable, brain-penetrable Autotaxin inhibitor with IC50 of 1 nM.

Packing	Price	Stock
2 mg	$278	In stock
5 mg	$458	In stock
10 mg	$758	In stock
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Biological Activity

BIO-32546 (BIO 32546) is a potent, selective, orally bioavailable, brain-penetrable Autotaxin inhibitor with IC50 of 1 nM.
BIO-32546 inhibits plasna hLPA level with IC50 of 53 nM.

Physicochemical Properties

M.Wt	543.55
Formula	C28H31F6NO3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Month
Shipping
Solubility	10 mM in DMSO (5.4 mg/mL)
Chemical Name/SMILES	8-[(1S)-1-[8-(Trifluoromethyl)-7-[[cis-4-(trifluoromethyl)cyclohexyl]oxy]-2-naphthalenyl]ethyl]-8-azabicyclo[3.2.1]octane-3-carboxylic acid

References

1. Bin Ma, et al. ACS Med Chem Lett. 2021 Jun 14;12(7):1124-1129.

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BIO-32546 (BIO 32546)

Biological Activity

Physicochemical Properties

References

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