PAT-347 | Autotaxin inhibitor | Probechem Biochemicals

Chemical Structure : PAT-347

Catalog No.: PC-23706Not For Human Use, Lab Use Only.

PAT-347 is a highly potent, selective inhibitor of autotaxin (ATX) with IC50 of 0.3 nM.

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Biological Activity

PAT-347 is a highly potent, selective inhibitor of autotaxin (ATX) with IC50 of 0.3 nM.

M.Wt	538.99
Formula	C28H21ClF2N2O3S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3-[[6-Chloro-7-fluoro-2-methyl-1-[2-oxo-2-(spiro[cyclopropane-1,3′-indolin]-1′-yl)ethyl]-1H-indol-3-yl]thio]-2-fluorobenzoic acid

1. Stein AJ, et al. Mol Pharmacol. 2015 Dec;88(6):982-92.

2. Salgado-Polo F, et al. Cancers (Basel). 2019 Oct 16;11(10):1577.