Autotaxin inhibitor 12 |CAS:1613513-14-6 Probechem Biochemicals

You are here:Home-Chemical Inhibitors & Agonists-Wnt/Notch/Hedgehog-Autotaxin-Autotaxin inhibitor 12

Chemical Structure : Autotaxin inhibitor 12

Autotaxin inhibitor 12

Catalog No.: PC-35168Not For Human Use, Lab Use Only.

Autotaxin inhibitor 12 is a highly potent, selective, orally-bioavailable inhibitor of autotaxin with IC50 of 3.1 nM in choline release assays.

Packing	Price	Stock	Quantity
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote
200 mg		Get quote

Get Quotation Now

* Please select Quantity before adding items.

or Bulk Inquiry

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Autotaxin inhibitor 12 is a highly potent, selective, orally-bioavailable inhibitor of autotaxin with IC50 of 3.1 nM in choline release assays.
Autotaxin inhibitor 12 shows ATX inhibition of IC50 9 nM in an in vitro serum assay, measuring 18:1 LPA levels by LCMS.
Autotaxin inhibitor 12 concentration-dependently inhibits autotaxin and formation of LPA in vivo.

Physicochemical Properties

M.Wt	440.325
Formula	C19H23Cl2N5O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3,5-dichlorobenzyl 4-(4-(1H-1,2,3-triazol-4-yl)butanamido)piperidine-1-carboxylate

References

1. Thomson CG, et al. Bioorg Med Chem Lett. 2018 May 21. pii: S0960-894X(18)30431-1.

Overnight Delivery
Fast & Safe Delivery Worldwide
Rewards Program

About Us

Our Services

Site Map

Join with Us
Product Use Citations

Pharmacological Glossary Abbreviations

Abbreviations

Quality Manual

Inquiry Form
How to Order

Terms & Conditions

Credit Card Payment

Shipping Rates & Policies

Privacy Policy
sales@probechem.com