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Chemical Structure : Avotaciclib
CAS No.: 1983983-41-0
Catalog No.: PC-38340Not For Human Use, Lab Use Only.
Avotaciclib (BEY1107) is a potent, selective CDK1 (Cyclin-Dependent Kinase 1) inhibitor, inhibits self-replication of cancer stem cells and is a candidate for pancreatic cancer treatment.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $198 | In stock | |
| 10 mg | $298 | In stock | |
| 25 mg | $498 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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Avotaciclib (BEY1107) is a potent, selective CDK1 (Cyclin-Dependent Kinase 1) inhibitor, inhibits self-replication of cancer stem cells and is a candidate for pancreatic cancer treatment.
CDK1 is a cell cycle control protein involved in cell division process, blocks G2/M phase in cell division, and eliminates cancer stem cells.
BEY1107 not only controls the cell division of cancer cells but also may overcome the tolerance on anti-cancer drugs with targeting mechanism by eliminating cancer stem cells.
BEY1107 showed synergistic effects of inhibiting metastasis of cancer cell combined with gemcitabine for pancreatic cancer.
| M.Wt | 281.279 | |
| Formula | C13H11N7O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
2,6-bis(2-aminopyrimidin-4-yl)pyridin-3-ol |
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1. Wang Q, et al. NPJ Precis Oncol. 2023 Jun 13;7(1):58.
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