Chemical Structure : Azosemide
CAS No.: 27589-33-9
Catalog No.: PC-35345Not For Human Use, Lab Use Only.
Azosemide (Azosemidum) is a potent Na-K-Cl Cotransporter NKCC1 with IC50 of 0.246 and 0.197 uM for hNKCC1A and NKCC1B, being about 4-times more potent than bumetanide.
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Azosemide (Azosemidum) is a potent Na-K-Cl Cotransporter NKCC1 with IC50 of 0.246 and 0.197 uM for hNKCC1A and NKCC1B, being about 4-times more potent than bumetanide.
Azosemide is a high-ceiling loop diuretic agent used to treat hypertension, edema, and ascites.
M.Wt | 370.83 | |
Formula | C12H11ClN6O2S2 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
2-chloro-5-(2H-tetrazol-5-yl)-4-(thiophen-2-ylmethylamino)benzenesulfonamide |
1. Hampel P, et al. Sci Rep. 2018 Jun 29;8(1):9877.
2. Harada K, et al. J Cardiovasc Pharmacol. 2009 Jun;53(6):468-73.
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