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Request The Product List ofNa-K-Cl Cotransporter (NKCC) Na-K-Cl Cotransporter (NKCC)

Cat. No. Product Name Information
PC-72596

STS66

NKCC1 inhibitor

STS66 is a novel BBB-penetrant Na+-K+-Cl- cotransporter 1 (NKCC1) inhibitor, reduces brain damage in mice after ischemic stroke.
PC-72425

ARN24092

NKCC1 inhibitor

ARN24092 (ARN-4092) is a potent, selective inhibitor of Na+-K+-Cl- importer NKCC1, shows significant dose-dependent inhibition of NKCC1 in the Ca2+ influx assay (51.9% at 100 uM).
PC-72424

ARN23746

NKCC1 inhibitor

ARN23746 (ARN-23746) is a potent, selective inhibitor of Na+-K+-Cl- importer NKCC1, shows NKCC1 inhibition 31.8% at 10 uM, and 95.2% at 100 uM in the Cl− influx assay on NKCC1-transfected HEK293 cells.
PC-35345

Azosemide

NKCC1 inhibitor

Azosemide (Azosemidum) is a potent Na-K-Cl Cotransporter NKCC1 with IC50 of 0.246 and 0.197 uM for hNKCC1A and NKCC1B, being about 4-times more potent than bumetanide.
PC-45286

Bumetanide

NKCC inhibitor

Bumetanide (Ro 10-6338, PF-1593) is an inhibitor of Na(+)-K(+)-2Cl(-) co-transporter (NKCC) with an IC50 of 0.6 uM.

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