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Chemical Structure : B-I09
CAS No.: 1607803-67-7
Catalog No.: PC-47078Not For Human Use, Lab Use Only.
B-I09 is a cell permeable IRE-1 RNase inhibitor with IC50 of 1.23 uM, inhibits IRE-1/XBP1 pathway, inhibits growth of human chronic lymphocytic leukemia (CLL) cells both in vitro and in vivo.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $118 | In stock | |
| 10 mg | $188 | In stock | |
| 25 mg | $298 | In stock | |
| 50 mg | $458 | In stock | |
| 100 mg | Get quote |
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B-I09 is a cell permeable IRE-1 RNase inhibitor with IC50 of 1.23 uM, inhibits IRE-1/XBP1 pathway, inhibits growth of human chronic lymphocytic leukemia (CLL) cells both in vitro and in vivo.
| M.Wt | 303.31 | |
| Formula | C16H17NO5 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
7-(1,3-Dioxan-2-yl)-1,2,3,4-tetrahydro-8-hydroxy-5H-[1]benzopyrano[3,4-c]pyridin-5-one |
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1. Chih-Hang Anthony Tang, et al. J Clin Invest. 2014 Jun;124(6):2585-98.
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