Chemical Structure : BAY-549
CAS No.:
867017-68-3
BAY-549
(BAY549, Azaindole-1, Azaindole 1)
Catalog No. : PC-42519Not For Human Use, Lab Use Only.
A potent, highly selective, ATP-competitive ROCK inhibitor with IC50 of 0.5/1.1 nM for ROCK1/ROCK2 respectively.
Packing Price Stock Quantity 2 mg $138 In stock 0 1 2 3 4 5 5 mg $218 In stock 0 1 2 3 4 5 10 mg $358 In stock 0 1 2 3 4 5 25 mg $588 In stock 0 1 2 3 4 5 50 mg Get quote 0 1 2 3 4 5 100 mg Get quote 0 1 2 3 4 5
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-4251901
Biological Activity
BAY-549 (Azaindole-1) is a potent, highly selective, ATP-competitive ROCK inhibitor with IC50 of 0.5/1.1 nM for ROCK1/ROCK2 respectively.
Physicochemical Properties
M.Wt
402.7852
Formula
C18H13ClF2N6O
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
2,4-Pyrimidinediamine, 6-chloro-N4-[3,5-difluoro-4-[(3-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl)oxy]phenyl]-
References
1. Kast R, et al. Br J Pharmacol.
2. Pankey EA, et al. Can J Physiol Pharmacol
3. Lasker GF, et al. Urology
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