Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.
EN | CN

Product Inquiry: sales@probechem.com
Order/PO receiving: order@probechem.com

You are here:Home-Chemical Inhibitors & Agonists-Epigenetics-Histone Methyltransferase (HMTase)-BAY-6035
BAY-6035

Chemical Structure : BAY-6035

CAS No.: 2247890-13-5

Add to Favorites

BAY-6035 (BAY6035)

Catalog No.: PC-63250Not For Human Use, Lab Use Only.

BAY-6035 is a potent, peptide-competitive inhibitor of histone methyltransferase SMYD3, inhibits in vitro methylation of MEKK2 peptide with IC50 of 88 nM, >100-fold selectivity over other HMTases.

Packing Price Stock Quantity
100 mg Get quote
250 mg Get quote
500 mg Get quote
1 g Get quote
Get Quotation Now
* Please select Quantity before adding items.
 or Bulk Inquiry

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    BAY-6035 is a potent, peptide-competitive inhibitor of histone methyltransferase SMYD3, inhibits in vitro methylation of MEKK2 peptide with IC50 of 88 nM, >100-fold selectivity over other HMTases; inhibits the methylation of MEKK2 in cells with IC50 of 70 nM.

    Physicochemical Properties

    M.Wt 396.491
    Formula C22H28N4O3
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    (2S)-1-(3-azabicyclo[3.1.0]hexane-3-carbonyl)-N-(2-cyclopropylethyl)-2-methyl-4-oxo-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepine-7-carboxamide

    References

    1, Stefan Gradl, et al. SLAS Discov. 2021 Sep;26(8):947-960.

    Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

    Contact Us sales@probechem.com

    Bulk Inquiry

    * Indicates a Required FieldYour information is safe with us.

    • *Product name:
    • *Applicant name:
    • *Email address:
    • *Organization name:
    • *Requested quantity:
    • *Country:
    • *Additional Information:

    Get Quote

    * Indicates a Required FieldYour information is safe with us.

    • *Product name:
    • *Applicant name:
    • *Email address:
    • *Organization name:
    • *Requested quantity:
    • *Country:
    • Additional Information: