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Chemical Structure : BAY 1892005
CAS No.: 2036352-13-1
Catalog No.: PC-49086Not For Human Use, Lab Use Only.
BAY 1892005 is a small molecule that modulate mutant p53 condensation and nuclear accumulation, binds covalently to mutant p53R175H and p53Y220C and shows stabilization of p53WT and p53Y220C, exhibits anti-proliferative activity in a set of cell lines with different p53 mutation status with low-uM IC50 values.
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|---|---|---|---|
| 5 mg | $248 | In stock | |
| 10 mg | $398 | In stock | |
| 25 mg | $598 | In stock | |
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| 100 mg | Get quote |
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BAY 1892005 is a small molecule that modulate mutant p53 condensation and nuclear accumulation, binds covalently to mutant p53R175H and p53Y220C and shows stabilization of p53WT and p53Y220C。
BAY 1892005 exhibits anti-proliferative activity in a set of cell lines with different p53 mutation status with low-uM IC50 values.
| M.Wt | 270.706 | |
| Formula | C11H8ClFN2OS | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
2-chloro-N-(4-(2-fluorophenyl)thiazol-2-yl)acetamide |
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1. Clara Lemos, et al. iScience. 2020 Sep 25; 23(9): 101517.
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