BAY 249716 | p53 modulator | Probechem Biochemicals

Chemical Structure : BAY 249716

CAS No.: 696628-24-7

BAY 249716 (BAY249716)

Catalog No.: PC-49087Not For Human Use, Lab Use Only.

BAY 249716 is a small molecule that modulate mutant p53 condensation, showed significant stabilization of all three p53 protein variants, p53WT p53R175H and p53Y220C.

Packing	Price	Stock
5 mg	$128	In stock
10 mg	$198	In stock
25 mg	$348	In stock
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Biological Activity

BAY 249716 is a small molecule that modulate mutant p53 condensation, showed significant stabilization of all three p53 protein variants, p53WT p53R175H and p53Y220C.
BAY 249716 exhibits anti-proliferative activity in a set of cell lines with different p53 mutation status with low-uM IC50 values.

Physicochemical Properties

M.Wt	288.753
Formula	C13H9ClN4S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(5-chloropyridin-2-yl)-4-(pyridin-2-yl)thiazol-2-amine

References

1. Clara Lemos, et al. iScience. 2020 Sep 25; 23(9): 101517.

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BAY 249716 (BAY249716)

Biological Activity

Physicochemical Properties

References

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