BC-DXI-843

Chemical Structure : BC-DXI-843

CAS No.: 2421117-98-6

Catalog No.: PC-23516Not For Human Use, Lab Use Only.

BC-DXI-843 is a potent and specific AIMP2-DX2 inhibitor with IC50 og 0.92 uM, >100-fold selectivity over AIMP2.

Packing	Price	Stock
5 mg	$98	In stock
10 mg	$148	In stock
25 mg	$258	In stock
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Biological Activity

BC-DXI-843 is a potent and specific AIMP2-DX2 inhibitor with IC50 og 0.92 uM, >100-fold selectivity over AIMP2.
BC-DXI-843 suppresses cancer cell proliferation in a DX2-dependent manner with EC50 of 1.2 uM in A549 cells.

Physicochemical Properties

M.Wt	546.66
Formula	C28H26N4O4S2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-3-(1H-Indol-3-yl)-N-(4-(4-methoxyphenyl)thiazol-2-yl)-2-(4-methylphenylsulfonamido)propanamide

References

1. Aneesh Sivaraman, et al. J Med Chem. 2020 May 28;63(10):5139-5158.

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BC-DXI-843

Biological Activity

Physicochemical Properties

References

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