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BCATc inhibitor 2

Chemical Structure : BCATc inhibitor 2

CAS No.: 406191-34-2

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BCATc inhibitor 2 (Bi2, BCAT1 inhibitor 2)

Catalog No.: PC-22799Not For Human Use, Lab Use Only.

BCATc inhibitor 2 (Bi2) is a specific inhibitor of cytosolic branched-chain aminotransferase (BCATc, BCAT1) with IC50 of 0.2/ 0.8 uM for rat/human BCATc respectively, weakly inhibits rat mitochondrial isoenzyme rBCATm.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

BCATc inhibitor 2 (Bi2) is a specific inhibitor of cytosolic branched-chain aminotransferase (BCATc, BCAT1) with IC50 of 0.2/ 0.8 uM for rat/human BCATc respectively, weakly inhibits rat mitochondrial isoenzyme rBCATm.

Physicochemical Properties

M.Wt 418.77
Formula C16H10ClF3N2O4S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

5-chloro-N'-[2-(trifluoromethyl)phenyl]sulfonyl-1-benzofuran-2-carbohydrazide

References

1. Caballero, J., et al. Mol. Divers 13, 493–500 (2009).

2. Lain-Yen Hu, et al. Bioorg Med Chem Lett. 2006 May 1;16(9):2337-40.

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