Catalog No.: PC-70108Not For Human Use, Lab Use Only.
BCI-121 (BCI121) is a substrate-competitive SMYD3 inhibitor that significantly inhibits SMYD3-substrate interaction and chromatin recruitment and is effective in reducing proliferation in various cancer cells types.
BCI-121 (BCI121) is a substrate-competitive SMYD3 inhibitor that significantly inhibits SMYD3-substrate interaction and chromatin recruitment and is effective in reducing proliferation in various cancer cells types.
BCI-121 impairs SMYD3-mediated H4 in vitro methylation, reduced proliferation of HT29 and HCT116 cells.
BCI-121 reproduces the effects of SMYD3-targeted RNAi.
