BCL3ANT | Bcl-3 inhibitor | Probechem Biochemicals

Chemical Structure : BCL3ANT

BCL3ANT (NSC-659509, NSC659509)

Catalog No.: PC-21687Not For Human Use, Lab Use Only.

BCL3ANT (NSC-659509) is a small molecule inhibitor of Bcl-3-mediated cyclin D1 expression, reduces cyclin D1 luciferase activity in Bcl-3-overexpressing melanoma cells with IC50 of 40.4 uM.

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Biological Activity

BCL3ANT (NSC-659509) is a small molecule inhibitor of Bcl-3-mediated cyclin D1 expression, reduces cyclin D1 luciferase activity in Bcl-3-overexpressing melanoma cells with IC50 of 40.4 uM.
BCL3ANT (NSC-659509) interferes with Bcl-3-mediated cyclin D1 promoter activity.
BCL3ANT (NSC-659509) (50 μM) inhibits melanoma cell proliferation and migration.

Physicochemical Properties

M.Wt	357.21
Formula	C13H10Cl2N4O2S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(((4-(3,4-dichlorophenyl)thiazol-2-yl)amino)methylene)malonamide

References

1. Saamarthy K, et al. BMC Cancer. 2024 Jan 18;24(1):103.

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BCL3ANT (NSC-659509, NSC659509)

Biological Activity

Physicochemical Properties

References

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