BDM35899

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Chemical Structure : BDM35899

Catalog No.: PC-26432Not For Human Use, Lab Use Only.

BDM35899 is a small activator of insulin degrading enzyme (IDE) with pEC50 of 5.3, binds to polyanion-binding site of IDE, activates both Aβ and insulin hydrolysis by IDE, decreases glucose-stimulating insulin secretion in β-pancreatic cells.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Physicochemical Properties

M.Wt	456.58
Formula	C22H24N4O3S2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	4-[1-(thiophene-2-sulfonyl)-1H-indol-3-yl]-N-(3-imidazole-1-yl-propyl)-butyramide

References

1. Nicolas Kraupner, et al. Eur J Med Chem. 2022 Jan 15:228:113982.

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BDM35899

Biological Activity

Physicochemical Properties

References

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