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BI 1595043

Chemical Structure : BI 1595043

CAS No.: 2412577-05-8

BI 1595043 (BI-1595043)

Catalog No.: PC-25561Not For Human Use, Lab Use Only.

BI 1595043 is a potent, selective and orally bioavailable Vanin (vanin‐1 and vanin‐2) inhibitor, demonstrates promising effects on epithelial cell protection and reduction of inflammatory mediators in preclinical studies.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

BI 1595043 is a potent, selective and orally bioavailable Vanin (vanin‐1 and vanin‐2) inhibitor, demonstrates promising effects on epithelial cell protection and reduction of inflammatory mediators in preclinical studies.

Physicochemical Properties

M.Wt 396.47
Formula C22H25FN4O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-[(3S)-1-[(2R)-2-(4-fluorophenyl)-2-methyl-1H,2H,3H-pyrrolo[2,3-b]pyridine-5-carbonyl]pyrrolidin-3-yl]-N-methylacetamide

References

1. Anjli Kukreja, et al. Clin Transl Sci. 2025 Sep;18(9):e70285.

2. Patent WO2020043658 A1.

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