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BI 639667

Chemical Structure : BI 639667

CAS No.: 1295298-26-8

BI 639667 (BI639667;BI-639667)

Catalog No.: PC-35039Not For Human Use, Lab Use Only.

BI 639667 (BI639667) is a potent and selective antagonist of human CCR1 with binding IC50 of 5.4 nM, inhibits chemotaxis with IC50 of 2.4 nM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

BI 639667 (BI639667) is a potent and selective antagonist of human CCR1 with binding IC50 of 5.4 nM, inhibits chemotaxis with IC50 of 2.4 nM.
BI 639667 shows good physico-chemical and pharmacokinetic properties.

Physicochemical Properties

M.Wt 451.476
Formula C22H18FN5O3S
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1-(4-fluorophenyl)-N-(1-(2-(methylsulfonyl)pyridin-4-yl)cyclopropyl)-1H-pyrazolo[3,4-c]pyridine-4-carboxamide

References

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