BIO
(6BIO;6-BIO;GSK 3 IX;GSK 3 Inhibitor IX;MLS 2052;MLS2052)
Catalog No.: PC-42664Not For Human Use, Lab Use Only.
BIO (6BIO, GSK-3 Inhibitor IX, MLS 2052) is a cell-permeable derivative of 6-bromoindirubin that displays selective inhibition of GSK-3 with IC50 of 5 nM.
BIO (6BIO, GSK-3 Inhibitor IX, MLS 2052) is a cell-permeable derivative of 6-bromoindirubin that displays selective inhibition of GSK-3 with IC50 of 5 nM.
BIO also inhibit CDK1/Cyclin B and CDK5/p25 (IC50, 320 nM and 83 nM).
BIO maintains the undifferentiated phenotype in HESCs and MESCs, sustains the expression of Oct-3/4, Rex-1 and Nanog.
BIO promotes proliferation in mammalian cardiomyocytes.
