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BIOD303

Chemical Structure : BIOD303

CAS No.: 91271-78-2

BIOD303 (BIOD 303;BIOD303)

Catalog No.: PC-60873Not For Human Use, Lab Use Only.

BIOD303 is a novel conformational modulator of α-synuclein with EC50 of 105 uM, potentially outcompetes spermine in binding to α-synuclein.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

BIOD303 is a novel conformational modulator of α-synuclein with EC50 of 105 uM, potentially outcompetes spermine in binding to α-synuclein.
BIOD303 binds to monomeric α-synuclein in vitro and significantly reduces α-synuclein aggregation in a neuronal cell culture model.

Physicochemical Properties

M.Wt 190.29
Formula C12H18N2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(3-(pyrrolidin-1-ylmethyl)phenyl)methanamine

References

1. Moree B, et al. J Biol Chem. 2015 Nov 13;290(46):27582-93.

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