BKI-1 | PfCDPK4 inhibitor | Probechem Biochemicals

Chemical Structure : BKI-1

BKI-1 (Bumped Kinase Inhibitor-1)

Catalog No.: PC-27936Not For Human Use, Lab Use Only.

BKI-1 (Bumped Kinase Inhibitor-1) is a highly potent bumped kinase inhibitor with IC50 of 4 nM for WT rPfCDPK4, potently inhibits the exflagellation of P. falciparum, does not block the proliferation of asexual parasites.

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Biological Activity

Physicochemical Properties

M.Wt	402.50
Formula	C23H26N6O
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3-(6-ethoxynaphthalen-2-yl)-1-(piperidin-4-ylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine

References

1. Ojo KK, et al. J Clin Invest. 2012 Jun;122(6):2301-5.

2. Oduselu GO, et al. Bioinform Biol Insights. 2026 Aug 28;20:11779322261483607.

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BKI-1 (Bumped Kinase Inhibitor-1)

Biological Activity

Physicochemical Properties

References

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