BKI-1841 | CpCDPK1 inhibitor | Probechem Biochemicals

Chemical Structure : BKI-1841

BKI-1841 (BKI 1841)

Catalog No.: PC-25202Not For Human Use, Lab Use Only.

BKI-1841 is a highly potent, specific Cryptosporidium calcium-dependent protein kinase 1 (CDPK1) inhibitor with IC50 of 3 nM (CpCDPK1, C. parvum CDPK1) and EC50 of 0.7 uM against C. parvum parasites in Nanoluciferase assays.

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Biological Activity

Physicochemical Properties

M.Wt	381.44
Formula	C20H23N5O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	5-amino-3-(2-ethoxyquinolin-6-yl)-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazole-4-carboxamide

References

1. Hulverson MA, et al. Antimicrob Agents Chemother. 2023 Apr 18;67(4):e0142522.

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BKI-1841 (BKI 1841)

Biological Activity

Physicochemical Properties

References

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