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BL-AD008

Chemical Structure : BL-AD008

CAS No.: 2660985-19-1

BL-AD008 (BL-AD 008)

Catalog No.: PC-35642Not For Human Use, Lab Use Only.

BL-AD008 (BL-AD 008) is a novel small molecule, dual-target activator targeting AMPK/ZIPK.

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    Biological Activity

    BL-AD008 (BL-AD 008) is a novel small molecule, dual-target activator targeting AMPK/ZIPK.
    BL-AD008 demonstrates remarkable anti-proliferative activities toward cervical cancer cells and could induce apoptosis by death-receptor and mitochondrial pathways.
    BL-AD008 also shows anti-tumor activities and induces apoptosis by targeting AMPK/ZIPK in vivo.

    Physicochemical Properties

    M.Wt 501.045
    Formula C28H25ClN4OS
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    (Z)-5-(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)ethyl)-3-benzylidene-6-chloroindolin-2-one

    References

    1. Fu L, et al. Oncotarget. 2015 Apr 10;6(10):8071-88.

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