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BMF-219

Chemical Structure : BMF-219

CAS No.: 2448172-22-1

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BMF-219 (Icovamenib, BMF219)

Catalog No.: PC-25566Not For Human Use, Lab Use Only.

BMF-219 (Icovamenib) is a potent, selective and covalent irreversible menin inhibitor, inhibits the growth of KRAS-mutated solid tumors with G12C, G12D, and G12V KRAS mutations.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

BMF-219 (Icovamenib) is a potent, selective and covalent irreversible menin inhibitor, inhibits the growth of KRAS-mutated solid tumors with G12C, G12D, and G12V KRAS mutations.

Physicochemical Properties

M.Wt 566.67
Formula C31H34N8O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(R)-4-((3-Acrylamidopiperidin-1-yl)methyl)-N-(4-(4-morpholino-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenyl)picolinamide

References

1. Brian Law, et al. Cancer Res (2022) 82 (12_Supplement): 2665.

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