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Chemical Structure : BMS-195614
Catalog No.: PC-20198Not For Human Use, Lab Use Only.
BMS-195614 (BMS195614) is a selective antagonist of neutral retinoic acid receptor RARα with Ki of 2.5 nM, antagonizes agonist-induced coactivator recruitment and moderately decreases SMRT binding to RAR, but does not significantly affect nuclear receptor corepressor binding.
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BMS-195614 (BMS195614) is a selective antagonist of neutral retinoic acid receptor RARα with Ki of 2.5 nM, antagonizes agonist-induced coactivator recruitment and moderately decreases SMRT binding to RAR, but does not significantly affect nuclear receptor corepressor binding.
| M.Wt | 448.52 | |
| Formula | C29H24N2O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. M Géhin, et al. Chem Biol. 1999 Aug;6(8):519-29.
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